Alizapride hydrochloride
CAS No. 59338-87-3
Alizapride hydrochloride( —— )
Catalog No. M15201 CAS No. 59338-87-3
Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
25MG | 43 | In Stock |
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50MG | 64 | In Stock |
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100MG | 102 | In Stock |
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200MG | 151 | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameAlizapride hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAlizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.
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DescriptionAlizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.(In Vivo):Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days) significantly reduces the bound IgG-sensitized erythrocytes with Splenic macrophages isolated from animals.
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In Vitro——
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In VivoAlizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days) significantly reduces the bound IgG-sensitized erythrocytes with Splenic macrophages isolated from animals. Animal Model:Male Duncan–Hartley guinea pigs Dosage:2.5, 5, 10, 25 μg/kg Administration:Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days)Result:Reduced the clearance of IgG-sensitized RBCs.
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Synonyms——
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorDopamine
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number59338-87-3
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Formula Weight351.83
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Molecular FormulaC16H21N5O2·HCl
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Purity>98% (HPLC)
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SolubilityWater: 70 mg/mL (198.95 mM); DMSO: 42 mg/mL (119.37 mM)
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SMILESCl.COC1=CC2=NNN=C2C=C1C(=O)NCC1CCCN1CC=C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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5-Benzyloxygramine
5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.
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Pramipexole
A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
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ONC206
ONC206 is an analogue of TRAIL inducer ONC201 and is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 also has broad-spectrum anti-tumor activity. ONC206 (Oncoceutics) is an imipiridone with nanomolar potency and analogue of ONC201, a selective dopamine receptor D2 (DRD2) antagonist currently being investigated in phase II clinical trials for serous endometrial cancer (SEC).??